Athletes are 2.5 times more likely than the general public to develop nail fungus, according to a study in the Journal of the American Academy of Dermatology. A condition that can disrupt training, change performance and end careers. However, until now, no thorough study has examined how nail fungus affects various sports.
Today, Case Western Reserve University and University Hospitals announced the launch of the first large-scale collaborative study focused on onychomycosis, a chronic fungal infection of the nails, among athletes.
While fans focus on visible injuries, nail fungus quietly undermines athletic performance in ways most people never consider.
When athletes are dealing with pain, nail damage or recurring infections, it can alter gait, reduce training consistency and ultimately affect competitive outcomes. This condition isn’t just about appearance; it’s about protecting athletes’ ability to perform at their best.”
James Voos, chairman of Orthopedic Surgery and the Jack and Mary Herrick Distinguished Chair at University Hospitals
The warm, moist environments created by intense training, restrictive footwear and shared facilities create perfect breeding grounds for fungal infections.
“There is very little data showing how common nail fungal infections are across different sports, despite the high risk among athletes,” said the study’s lead researcher Mahmoud Ghannoum, director of the Center for Medical Mycology at Case Western Reserve. “Our goal with this research is to better understand the epidemiology and general insights that will inform improved prevention, diagnosis and treatment strategies.”
The six-month study also includes UH Drusinsky Sports Medicine Institute-the healthcare partner of the Cleveland Ballet, Cleveland Browns and Cleveland Monsters-and Ortho Dermatologics, a division of Bausch Health.
These partners will help identify and recruit 100 to 200 collegiate and professional athletes, allowing researchers to gather data across multiple sports. They will also raise awareness, facilitate survey distribution and assist with athlete screening and optional nail sampling for follow-up studies.
“This research represents a critical step toward keeping athletes healthy, competitive and at the top of their game,” Ghannoum said. “Every athlete deserves to compete without preventable conditions holding them back.”
The study begins this month, with initial results expected by June. Athletes will be surveyed through an electronic questionnaire that asks about nail appearance, discomfort during training or competition, impact on performance and previous treatments. The anonymous survey captures how toenail fungal infections affect daily activities, confidence and athletic function.
Future study phases will focus on advanced diagnostic tools and enhanced treatment protocols with applications extending beyond professional athletics. The research could particularly benefit military personnel and other groups facing similar risks from repetitive foot trauma, shared equipment and challenging physical environments.
Case Western Reserve and the City of Cleveland are uniquely positioned for this research because it brings together a high-volume sports medicine environment, a leading medical mycology center and direct access to professional, collegiate and youth athletic organizations. This combination allows researchers to study onychomycosis in athletes at a scale and level of clinical detail that is rarely available elsewhere.
Source:
Case Western Reserve University















